What are some tips for managing lipodystrophy? Doctors must carefully consider and discuss with each person the possible benefits and risks of this treatmentīelow are answers to some frequently asked questions about lipodystrophy. Metreleptin is only available under a restricted program. Other side effects of metreleptin include: There is also a link between metreleptin and lymphoma. These may lead to infection and a loss of metabolic control. Some people have developed anti-metreleptin neutralizing antibodies after taking the medication. Metreleptin can have serious adverse effects, however. In 2014, the Food and Drug Administration (FDA) approved a leptin replacement therapy called metreleptin to help treat generalized lipodystrophy. They may also prescribe medications called statins to help manage high cholesterol. Many of these treatments focus on mitigating the conditions associated with lipodystrophy, such as:ĭoctors recommend a balanced diet and regular exercise to help a person maintain a moderate weight. There is no cure for lipodystrophy, but some treatments can prolong a person’s life and improve their quality of life. Treating lipodystrophy may require different specialists and other healthcare professionals working together. The loss of fat only occurs at the injection site, creating a small dimple or “crater.” Rotating the injection sites can help prevent localized lipodystrophy. This usually affects people who have repeated daily injections, such as regular insulin injections to manage diabetes. This does not reverse if the person stops taking antiretroviral medication. High active antiretroviral therapy-induced lipodystrophy is a rare form that occurs in some people who take antiretroviral medication to treat HIV.Ī person with this condition gradually loses fat from their arms, legs, and face. High active antiretroviral therapy-induced lipodystrophy It does not usually affect the lower limbs. The loss of fat usually occurs on the face, neck, and upper extremities. Acquired partial lipodystrophyĪcquired partial lipodystrophy (APL), or Barraquer-Simons syndrome, develops after birth. The condition is “acquired” because experts have not confirmed a genetic cause of it. It develops during adolescence and has a similar presentation to CGL. Other names for acquired generalized lipodystrophy are AGL and Lawrence syndrome. The body may store this around the face, neck, and abdomen. People with this type often begin to lose fat tissue during puberty.Ī person may progressively lose fat from their arms and legs. Familial partial lipodystrophyįamilial partial lipodystrophy (FPL) is also an inherited condition. This causes their arms and legs to appear thin and muscular. Infants with CGL have almost no subcutaneous fat, which is the layer of fat beneath the skin. It is present from birth, and infants begin losing weight a few weeks after birth. There are several types of lipodystrophy: Congenital generalized lipodystrophyĬongenital generalized lipodystrophy (CGL) is an inherited condition.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |